Wunderlich Syndrome From Lupus-Associated Vasculitis
Resource
Am. J. Kidney Dis., 61(1), 167-170
Journal
Am. J. Kidney Dis.
Journal Volume
61
Journal Issue
1
Pages
167-170
Date Issued
2013
Date
2013
Author(s)
Chao, Chia-Ter
Abstract
Spontaneous perinephric hemorrhage is a clinically rare life-threatening condition, also known as Wunderlich syndrome. Presentations can be variable, but patients typically display symptoms and signs including flank or abdominal pain, abdominal mass, and hypovolemia. It is important to diagnose the syndrome early because untreated cases carry a high mortality risk, and prompt intervention with an endovascular procedure or surgery is life saving. Causes range from anatomical anomalies, including vascular diseases (vasculitides and aneurysms) and renal tumors, to functional coagulation defect (bleeding tendency). The most common causes of Wunderlich syndrome are renal angiomyolipoma and renal cell carcinoma, constituting 60%similar to 70% of cases. Vascular causes of Wunderlich syndrome are infrequent, and the culprit most frequently is vasculitis resulting from polyarteritis nodosa. Other vasculitides presenting as Wunderlich syndrome are infrequent. We describe a 39-year-old woman with end-stage renal disease from lupus nephritis and spontaneous renal hemorrhage, ascribed to lupus-related vasculitis after serologic testing, computed tomography, and angiographic studies. Am J Kidney Dis. 61(1):167-170. (C) 2012 by the National Kidney Foundation, Inc.
Subjects
Lupus erythematosus
vasculitis
Wunderlich syndrome
Type
journal article
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