Anti-recoverin antibody positive Heidenhain variant CJD: a case report
Journal
Prion
Journal Volume
17
Journal Issue
1
Start Page
133
End Page
137
ISSN
1933-6896
Date Issued
2023
Author(s)
Abstract
The Heidenhain variant Creutzfeldt-Jakob disease (CJD) is characterized by isolated visual symptoms at disease onset, which may mimic numerous ophthalmological disorders. Anti-recoverin autoantibody can be found in patients with autoimmune-related retinopathies. The presence of this antibody with visual symptoms might be confusing in the early stages of the Heidenhain variant CJD. We describe the first case of an anti-recoverin antibody found in the Heidenhain variant CJD who presented with progressive blurred vision then memory deterioration proceeded later. This presentation reinforces the concept that the presence of the anti-recoverin antibody could not exclude the possibility of the Heidenhain variant of CJD in highly suspicious patients with initial isolated visual disturbance.
Subjects
Anti-recoverin antibody
Creutzfeldt-Jakob disease (CJD)
Heidenhain variant CJD
autoimmune-related retinopathies
isolated visual symptoms
SDGs
Type
journal article