Leukocytoclastic vasculitis with severe cardiac involvement in an infant: A case report
Journal
Clinical Rheumatology
Journal Volume
27
Journal Issue
7
Pages
945-947
Date Issued
2008
Author(s)
Abstract
Severe visceral involvement in leukocytoclastic vasculitis is rare. We report here the case of a 2-month-old male infant with leukocytoclastic vasculitis who initially presented with fever and skin purpura. Endomyocarditis with mitral valve regurgitation, multiple hepatic infarction, and pulmonary hemorrhage developed later. The patient was successfully managed with an aggressive treatment of high frequency oscillation ventilation and extracorporeal membrane oxygenation together with corticosteroid and azathioprine therapy for 3 months. Valvuloplasty was also performed due to irreversible damage of the mitral valve, although long-term oral anticongestive medications were also needed. ? Clinical Rheumatology 2008.
SDGs
Other Subjects
antibiotic agent; azathioprine; cardiovascular agent; corticosteroid; immunoglobulin; oxygen; steroid; article; artificial ventilation; case report; clinical feature; computer assisted tomography; congestive heart failure; continuous hemofiltration; differential diagnosis; disease severity; drug substitution; drug withdrawal; endocarditis; extracorporeal oxygenation; fever; heart disease; human; human tissue; infant; laboratory test; leukocytoclastic vasculitis; liver biopsy; liver disease; lung hemorrhage; male; mitral valve regurgitation; mitral valve repair; mucocutaneous lymph node syndrome; myocarditis; physical examination; priority journal; purpura; respiratory distress; treatment duration; Adrenal Cortex Hormones; Azathioprine; Balloon Dilatation; Extracorporeal Membrane Oxygenation; High-Frequency Ventilation; Humans; Immunosuppressive Agents; Infant; Male; Mitral Valve Insufficiency; Myocarditis; Vasculitis, Hypersensitivity
Type
journal article