Brain-derived neurotrophic factor contributes to neurogenesis after intracerebral hemorrhage: a rodent model and human study
Journal
Frontiers in cellular neuroscience
Journal Volume
17
Pages
1170251
Date Issued
2023
Author(s)
Lin, Ting-Chun
Tsai, Yi-Chieh
Chen, Yun-An
Wu, Chung-Che
Chiang, Yung-Hsiao
Kao, Chia-Hsin
Hsu, Yi-Hua
Chen, Kai-Yun
Abstract
Intracerebral hemorrhage (ICH) enhances neurogenesis in the subventricular zone (SVZ); however, the mechanism is not fully understood. We investigated the role of brain-derived neurotrophic factor (BDNF) in post-ICH neurogenesis in a rodent model and in patients with ICH using cerebrospinal fluid (CSF).
Subjects
brain-derived neurotrophic factor (BDNF); cerebrospinal fluid; intracerebral hemorrhage (ICH); neurogenesis; subventricular zone (SVZ)
SDGs
Type
journal article