Effect of Prolonged Radiation Exposure on the Thyroid Gland of Residents Living in 60co-Contaminated Rebar Buildings
Resource
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY v.77 n.11 pp.1117-1122
Journal
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
Journal Volume
v.77
Journal Issue
n.11
Pages
1117-1122
Date Issued
2001
Date
2001
Author(s)
CHANG, TIEN-CHUN
Abstract
Purpose : To evaluate prolonged low dose-rate gamma - exposure effects on the thyroid glands of residents living in Co-60-contaminated steel buildings. Materials and methods : Physical examination and ultrasonography of the thyroid, determination of thyroid function and anti -thyroid microsomal antibodies were performed for 1346 residents. Ultrasound-guided aspiration cytology was done for thyroid nodules. The study subjects were stratified by age at examination (less than or equal to 15 and >15 years), sex and exposure dose to the body. Dose-response data on the prevalence of various thyroid diseases were analysed by the multiple logistic regression analysis. Results and conclusions : The prevalence of simple goitre was related to the exposure with a dose- response relationship for males of all ages, and for females of less than or equal to 15 years . There was a biological gradient of thyroid cyst prevalence with the increase in exposure dose for females of all ages. The prevalence of elevated serum tri-iodothyronine level showed a dose- response relationship for males of less than or equal to 15 years. A significant increase in thyroid abnormalities with dose was observed for males of all ages, and for females of less than or equal to 15 years.
Subjects
CONTAMINATED REBAR
CHERNOBYL DISASTER
CHILDREN
ADOLESCENTS
ABNORMALITIES
PREVALENCE
Type
journal article