Dual Ion-Selective Membrane Deposited Ion-Sensitive Field-Effect Transistor (DISM-ISFET) Integrating Whole Blood Processing Microchamber for In Situ Blood Ion Testing
Journal
Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
Journal Volume
2023-January
ISBN
9781665493086
Date Issued
2023-01-01
Author(s)
Abstract
Blood ion testing is one of the methods that is commonly used as of monitoring immune status and providing lots of physiological information for disease diagnosis. We proposed a microfluidic device integrating dual ion-selective membranes and dual-gate ion-sensitive field-effect transistor (DISM-ISFET) for whole blood processing and blood ion concentrations monitoring. In this system, the Anti-D-coated trench array and filter membrane embedded microchamber greatly shorten the serum extraction time to 4 min. Besides, the DISM-ISFET array sensor enables simultaneous Na+ and K+ ion sensing in 10 min. The above features make this fully integrated and portable system a rapid and sensitive tool for in situ blood ion concentration diagnosis.
Subjects
blood ion concentration test | ion-selective membrane (ISM) | ion-sensitive field-effect transistor (ISFET)
SDGs
Type
conference paper