Xeniaphyllane-Derived Terpenoids from the Formosan Soft Coral Sinularia gibberosa
Resource
CHEMICAL & PHARMACEUTICAL BULLETIN 55 (10): 1471
Journal
Chemical and Pharmaceutical Bulletin
Journal Volume
55
Journal Issue
10
Pages
1471-1475
Date Issued
2007
Date
2007
Author(s)
Abstract
New xeniaphyllane-derived metabolites (1-7) were isolated from the EtOAc extract of the Formosan soft coral Sinularia gibberosa. The structures and relative configurations of these compounds were elucidated on the basis of extensive spectroscopic analysis (including 2D NMR) and by comparison of their spectral data with those of related compounds. In vitro cytotoxic evaluation of the above metabolites towards a limited panel of cancer cell lines is also described. ? 2007 Pharmaceutical Society of Japan.
Subjects
Sinularia gibberosa; Soft coral; Xeniaphyllane-derived
SDGs
Other Subjects
gibberosin g; gibberosin h; gibberosin i; gibberosin j; gibberosin k; gibberosin l; gibberosin m; natural product; terpenoid derivative; unclassified drug; xeniaphyllane; antineoplastic activity; article; breast carcinoma; cancer cell culture; cancer research; cell strain HepG2; controlled study; coral; cytotoxicity; cytotoxicity test; drug isolation; human; human cell; in vitro study; liver cell carcinoma; lung carcinoma; nuclear magnetic resonance; Sinularia gibberosa; spectroscopy; Acetates; Animals; Anthozoa; Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Molecular Structure; Sesquiterpenes; Terpenes
Type
journal article
File(s)![Thumbnail Image]()
Loading...
Name
69.pdf
Size
121.55 KB
Format
Adobe PDF
Checksum
(MD5):dc9b962cb125099d8865f99ece44487a