Enhanced non-endocytotic uptake of mesoporous silica nanoparticles by shortening the peptide transporter arginine side Chain
Journal
ACS Applied Materials and Interfaces
Journal Volume
5
Journal Issue
23
Pages
12244-12248
Date Issued
2013
Author(s)
Abstract
Mesoporous silica nanoparticles (MSNs) are multifunctional nanocarriers with potential biomedical applications. However, MSNs are frequently trapped in endosomes upon cellular uptake through endocytosis, requiring endosomal escape. Herein, enhanced nonendocytosis was observed for 300 nm MSNs by conjugating peptides with noncanonical arginine analogs.
SDGs
Type
journal article