Synthesis of Methacrylic Acid and Ferulic Acid Copolymer with Antioxidant Properties Using Supercritical Carbon Dioxide
Date Issued
2010
Date
2010
Author(s)
Huang, Tzu-Ling
Abstract
The unique and tunable fluid properties of supercritical carbon dioxide have been used in polymer synthesis or polymer process recently, especially, the materials for medical, pharmaceutical, and food technology. In this work, polymeric antioxidants were synthesized for the first time in supercritical carbon dioxide. The strategy that using supercritical carbon dioxide as green solvent, methacrylic acid(MAA) as monomer, antioxidant ferulic acid(FA) as comonomer and ethylene glycol dimethacrylate (EGDMA) as crosslinker is suggested, and addition polymerization proceeded with initiator AIBN under supercritical carbon dioxide (65℃, 20 MPa, 24 hrs). The two forms of polymeric antioxidants, linear copolymer PMAA-FA and network polymer PMAA-FA-EGDMA, were obtained successfully. The chemical properties could be identified by FTIR, UV-Vis spectrums and 1H NMR, and the degradation temperature of polymeric antioxidants were studied by TGA. Antioxidant ability measured by DPPH assay of PMAA-FA and PMAA-FA-EGDMA performed about 89.4 % and 72.9 %. Compared with that of the control polymers synthesized in the absence of antioxidant molecules, the antioxidant activity of the two polymeric antioxidants was effectively elevated. SEM images showed the size of products were about 0.24~0.49 μm with aggregated morphology. The two forms of polymeric antioxidants could be useful in pharmaceutical and medical applications.
Subjects
supercritical carbon dioxide
supercritical polymerization
ferulic acid
methacrylic acid
Type
thesis
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