台北-紐約腦中風研究計畫(2/2)
Date Issued
2000
Date
2000
Author(s)
鄭建興
DOI
892314B002030
Abstract
Purpose: Cerebrovascular disease (CVD) is still one of most important causes of death and physical/mental disabilities in Chinese populations. Is there geographic differences of stroke existed among different Chinese inhabitants? This study aimed to assess he patterns of CVD, and the distribution of risk factors in different types of CVD in Chinese patients living in Taipei and
New York.
Methods: Consecutive Chinese patients with acute stroke or transient ischemic attack from the National Taiwan University Hospital (NTUH) in Taipei and the New York University Downtown Hospital (NYUDTH) in New York were recruited into this study. Types of stroke (cerebral infarct, Cl; cerebral hemorrhage, CH; subarachnoid hemorrhage, SAH; and TIA) and subtypes of CI were diagnosed according to clinical and neuroimaging findings. CVD risk factors and conditions associated with carotid atherosclerosis were obtained from patient. An ultrasonographic assessment of extracranial carotid artery atherosclerosis and stenosis was carried out, The t-test in continuous variables and the Mantel-Haenszel x2 test in categorical risk factors are used to find the differences between CVD patients living in Taipei and New York. Results :During 1995-98, there were 3,117 and 427 patients, aged l8 years, with first-ever stroke recruited into NTUH and NYUDTH stroke registries respectively. For NTUH patients, 2057 (66%), 144 (5%), 718 (23%) and 197 (6%) were belonging to CI, TIA, CH and SAH in the order. For NYUDTH, 292 (68%), 40 (9%), 87 (20%) and 13 (3%) were belonging to CI, TIA, CM and SAM in the order. The average age of stroke was older in NYUDTH patients than NTUH patients (71 y vs 63 y). The frequencies of hypertension (74% vs 63%), DM (30% vs 26%), AF (18% vs 13%), were higher in NYUDTH patients than NTUH patients. The frequencies of severe extracranial ICA stenosis (>50%) were similar between NYDTH and NTUH patients with CI (both were 11%). The 30-day case-fatality of overall patients were 11.1% and 10.5% at NTUH and NYUDTI-I respectively.
Conclusions :There were some difference of stroke types and their risk factors between Chinese populations in Taipei and New York. Further investigations are needed for clarification of the influence of environment or life style on CVD.
Subjects
Cerebrovascular disease
Chinese
Stroke registry
Racial difference
Publisher
臺北市：國立臺灣大學醫學院神經科
Type
journal article
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