Effects of non-physiological blood pressure artefacts on cerebral autoregulation
Journal
Medical Engineering and Physics
Journal Volume
47
Pages
218-221
Date Issued
2017
Author(s)
Abstract
Cerebral autoregulation refers to the brain's regulation mechanisms that aim to maintain the cerebral blood flow approximately constant. It is often assessed by the autoregulation index (ARI). ARI uses arterial blood pressure and cerebral blood flow velocity time series to produce a ten-scale index of autoregulation performance (0 denoting the absence of and 9 the strongest autoregulation). Unfortunately, data are rarely free from various artefacts. Here, we consider four of the most common non-physiological blood pressure artefacts (saturation, square wave, reduced pulse pressure and impulse) and study their effects on ARI for a range of different artefact sizes. We show that a sufficiently large saturation and square wave always result in ARI reaching the maximum value of 9. The pulse pressure reduction and impulse artefact lead to more diverse behaviour. Finally, we characterized the critical size of artefacts, defined as the minimum artefact size that, on average, leads to a 10% deviation of ARI. ? 2017 IPEM
Subjects
Blood pressure
Blood vessels
Hemodynamics
Physiology
Tissue
Arterial blood pressure
Autoregulations
Cerebral autoregulation
Cerebral blood flow
Cerebral blood flow velocities
Critical size
Pulse pressure
Regulation mechanisms
Brain
arterial pressure
Article
artifact
artifact reduction
autoregulation
autoregulation index
brain blood flow
brain function
cerebral autoregulation
controlled study
human
human experiment
medical parameters
normal human
priority journal
pulse pressure
blood flow velocity
blood pressure
blood pressure measurement
brain circulation
evaluation study
homeostasis
physiology
procedures
reproducibility
sensitivity and specificity
Artifacts
Blood Flow Velocity
Blood Pressure
Blood Pressure Determination
Cerebrovascular Circulation
Homeostasis
Humans
Reproducibility of Results
Sensitivity and Specificity
SDGs
Type
journal article