Betaxolol versus propranolol for the control of tachycardia of hyperthyroidism
Journal
Tzu Chi Medical Journal
Journal Volume
15
Journal Issue
4
Pages
235-239
Date Issued
2003
Author(s)
Abstract
Objective: Betaxolol is a long-acting highly selective β-blocker. To the best of our knowledge, there has been no report about the use of betaxolol in hyperthyroidism. The aim of this study was to elucidate the effect of betaxolol versus propranolol, a short-acting, non-selective B-blocker, for the control of tachycardia of hyperthyroidism. Patients and Methods: We did a retrospective study on 132 untreated patients with typical clinical symptoms, signs of hyperthyroidism, and abnormal thyroid function tests. They were divided into 2 groups according to whether they were given propranolol or betaxolol. Heart rates were recorded at 1, 2, and 4 weeks from the date of initiation of the medication. Results: The betaxolol group showed better results than the propranolol group of a decreased heart rate at doses prescribed by physicians in the outpatient department after 1 and 2 weeks. No difference existed between these 2 groups after 4 weeks. There were no betaxolol-related side effects reported during the present study. Conclusions: Betaxolol is effective and has quick action for the control of tachycardia of hyperthyroidism, and may be used in addition to antithyroid drugs for treating patients with hyperthyroidism.
Subjects
Betaxolol; Hyperthyroidism; Propranolol; Tachycardia
SDGs
Other Subjects
antithyroid agent; beta adrenergic receptor blocking agent; betaxolol; propranolol; adolescent; adult; aged; article; asthma; bronchospasm; chronic bronchitis; combination chemotherapy; congestive heart failure; depression; disease exacerbation; dose response; dose time effect relation; drug choice; drug efficacy; drug mechanism; drug selectivity; exercise tolerance; female; hallucination; heart rate; human; hyperthyroidism; hypoglycemia; hypotension; major clinical study; male; neurotoxicity; nightmare; obsessive compulsive disorder; outpatient; peripheral ischemia; prescription; psychosis; retrospective study; side effect; symptomatology; tachycardia; thyroid function test
Type
journal article