Two dynamically competing factors determine the translation start site
Journal
Nature Structural & Molecular Biology
Journal Volume
2025
ISSN
1545-9993
1545-9985
Date Issued
2025-09-02
Author(s)
Chen, Yi-Lan
Abstract
To start, or not to start, that is the recurring question faced by eukaryotic ribosomes as they scan mRNA for translation start sites. A study now shows that two opposing initiation factors, which bind the ribosome in a mutually exclusive manner, assist in this decision-making process.
SDGs
Publisher
Springer Science and Business Media LLC
Type
other