Reduced mitochondrial DNA content correlate with poor clinical outcomes in cryotransfers with day 6 single euploid embryos
Journal
Frontiers in endocrinology
Journal Volume
13
Date Issued
2023-01-04
Author(s)
Chuang, Tzu-Hsuan
Chen, Chih-Yen
Kuan, Chin-Sheng
Lai, Hsing-Hua
Hsieh, Chia-Lin
Lee, Meng-Ju
Liang, Yi-Ting
Chang, Yu-Jen
Chen, Chien-Yu
Abstract
To investigate whether the mitochondrial DNA (mtDNA) content of a single biopsy at trophoblast correlates with the developmental potential and reproductive outcomes of blastocyst.
Subjects
blastocyst formation day; mitochondria; next-generation sequencing; preimplantation genetic testing for aneuploidy(PGT-A); single embryo transfer (SET)
Publisher
FRONTIERS MEDIA SA
Type
journal article