Anti-platelet aggregation constituents from Formosan Toddalia asiatica
Journal
Phytochemistry
Journal Volume
48
Journal Issue
8
Pages
1377-1382
Date Issued
1998
Author(s)
CHE-MING TENG
Abstract
Examination on the wood of Formosan Toddalia asiatica led to the isolation of 30 compounds, including coumarins, alkaloids, a benzoquinone and an amine. Among the isolates, (+/-)-toddanin and (-)-isocoreximine are new compounds, while cyclohexylamine was isolated for the first time from nature. The structures of the compounds were elucidated from spectroscopic data and chemical evidence. Bioassay-guided fractionation led to the isolation of seven compounds showing strong anti-platelet aggregation activity in vitro.
SDGs
Type
journal article