Age of First Arrhythmic Event in Brugada Syndrome: Data from the SABRUS (Survey on Arrhythmic Events in Brugada Syndrome) in 678 Patients
Journal
Circulation: Arrhythmia and Electrophysiology
Journal Volume
10
Journal Issue
12
Date Issued
2017
Author(s)
Milman A.
Andorin A.
Gourraud J.-B.
Sacher F.
Mabo P.
Kim S.-H.
Maeda S.
Takahashi Y.
Kamakura T.
Aiba T.
Conte G.
Leshem E.
Rahkovich M.
Hochstadt A.
Mizusawa Y.
Postema P.G.
Arbelo E.
Huang Z.
Denjoy I.
Giustetto C.
Wijeyeratne Y.D.
Napolitano C.
Michowitz Y.
Brugada R.
Casado-Arroyo R.
Champagne J.
Calo L.
Sarquella-Brugada G.
Tfelt-Hansen J.
Priori S.G.
Takagi M.
Veltmann C.
Delise P.
Corrado D.
Behr E.R.
Gaita F.
Yan G.-X.
Brugada J.
Leenhardt A.
Wilde A.A.M.
Brugada P.
Kusano K.F.
Hirao K.
Nam G.-B.
Probst V.
Belhassen B.
Abstract
BACKGROUND: Data on the age at first arrhythmic event (AE) in Brugada syndrome are from limited patient cohorts. The aim of this study is 2-fold: (1) to define the age at first AE in a large cohort of patients with Brugada syndrome, and (2) to assess the influence of the mode of AE documentation, sex, and ethnicity on the age at first AE. METHODS AND RESULTS: =0.003). Whites and Asians exhibited their AE at the same median age (43 years). CONCLUSIONS: SABRUS (Survey on Arrhythmic Events in Brugada Syndrome) presents the first analysis on the age distribution of AE in Brugada syndrome, suggesting 2 age cutoffs (16 and 70 years) that might be important for decision-making. It also allows gaining insights on the influence of mode of arrhythmia documentation, patient sex, and ethnic origin on the age at AE.
Publisher
Lippincott Williams and Wilkins
Type
journal article