Fulminant postirradiation soft tissue sarcoma
Journal
Clinical Nuclear Medicine
Journal Volume
34
Journal Issue
11
Pages
811-814
Date Issued
2009
Abstract
A 49-year-old man had a secondary primary esophageal squamous cell carcinoma that was treated with neoadjuvant concurrent chemoradiotherapy (CCRT). An unexpected fulminant postirradiation malignant fibrous histiocytoma developed in the irradiation field 2 months after the CCRT. After esophagectomy and adjuvant radiation therapy, widespread disease still occurred in 2 months and he died of tumor bleeding 2 months later. The serial diagnostic images were compared and revealed that fluoro-deoxy-glucose positron emission tomography (FDG PET) was more useful in distinguishing post-therapeutic change and tumor recurrence in the region after surgical and radiation therapy. This report is of a postirradiation sarcoma with a very short latent period.
SDGs
Type
journal article