An energy free passive pumping system for microfluidic device
Journal
22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
Journal Volume
4
ISBN
9781510897571
Date Issued
2018-01-01
Author(s)
Abstract
In this work, we are the first to generate a novel, energy free liquid delivery method utilizing by osmotic pressure in the microfluidic device. The semi-permeable biomimetic membrane properties, total transferred volume and flow rate were evaluated. A universal osmotic outlet plug is developed as a negative pressure for standard PMMA and PDMS microfluidic devices. The reverse salt flux is investigated to prove the biocompatibility of the osmotic outlet plug. We further demonstrated a precise single macrophages position application using osmotic outlet plug. This osmotic outlet plug provides similar functionality to traditional syringe pump but opens a great potential to make the portable device miniaturization to be true.
Subjects
Energy free liquid delivery method | Osmosis | Passive | Pumpless
Type
conference paper