Butyrate modulates adipose-derived stem cells isolated from polygenic obese and diabetic mice to drive enhanced immunosuppression
Journal
Cytotherapy
Journal Volume
23
Journal Issue
7
Pages
567-581
Date Issued
2021
Author(s)
Abstract
Background aims: Adipose-derived stem cells (ASCs) offer promising therapeutic possibilities for immunomodulation. Butyrate (BA) exerts potent anti-inflammatory effects and exhibits multiple regulatory functionalities in adipose tissue (AT). The authors a
SDGs
Other Subjects
amphiregulin; butyric acid; gamma interferon; histone H3; inducible nitric oxide synthase; interleukin 10; nitric oxide; nitric oxide synthase; transcription factor FOXP3; tumor necrosis factor; butyric acid derivative; adipose derived stem cell; animal c
Publisher
Elsevier B.V.
Type
journal article