The sandwich sign of nonlymphomatous origin
Journal
Journal of Clinical Ultrasound
Journal Volume
37
Journal Issue
4
Pages
212-214
Date Issued
2009
Author(s)
Abstract
Purpose. To investigate the etiologies of the sandwich sign other than lymphoma. Method. The images of 34 patients with sonographic sandwich sign over a 5-year period were retrospectively reviewed. The etiology was based on the pathologic report of mesenteric lymph nodes, or the presence of extensive metastatic disease in case of known advanced primary cancer or disappearance of the sign after specific treatments. Results. Malignancy accounted for the majority of cases (91%), and was divided into nonHodgkin's lymphoma (50%) and metastatic carcinomas (41%). Mycobacterium tuberculosis infection was diagnosed in a previously healthy patient, and 2 patients with acquired immunodeficiency syndrome had Mycobacterium avium-complex infection. The sandwich sign was 1 of the initial presentations in 11 cases with newly diagnosed malignancies, including 6 cases of nonHodgkin's lymphoma and 5 cases of metastatic carcinomas. Conclusion. Metastatic carcinomas, M. avium-complex, and M. tuberculosis infection may produce the sandwich sign. Searching for etiologies other than lymphoma is important in patients presenting with the sandwich sign. ? 2008 Wiley Periodicals, Inc.
SDGs
Other Subjects
adult; aged; article; cancer research; clinical article; clinical feature; controlled study; echography; female; human; male; mesentery lymph node; metastasis; Mycobacterium tuberculosis; nonhodgkin lymphoma; tuberculosis; cohort analysis; comparative study; Doppler flowmetry; lymph node; lymph node metastasis; lymphoma; mesentery; metastasis; methodology; middle aged; neoplasm; nonhodgkin lymphoma; pathology; retrospective study; sensitivity and specificity; tuberculosis; Adult; Aged; Aged, 80 and over; Cohort Studies; Female; Humans; Lymph Nodes; Lymphatic Metastasis; Lymphoma; Lymphoma, Non-Hodgkin; Male; Mesentery; Middle Aged; Neoplasm Metastasis; Neoplasms; Retrospective Studies; Sensitivity and Specificity; Tuberculosis; Ultrasonography, Doppler
Type
journal article