Prevention of Glutamate-Induced Neurodegeneration by Piceatannol via Mitochondrial Rescue In Vitro and In Vivo
Journal
Molecular Nutrition & Food Research
Date Issued
2023-04-30
Author(s)
Koh, Yen-Chun
Chok, Dickson
Chang, Chun-Han
Wu, Chia-Tung
Cheng, Ko-Chun
Nagabhushanam, Kalyanam
Ho, Chi-Tang
Abstract
Parkinson's disease is one of the neurodegenerative diseases that have no cure. Excitotoxicity induced by excess glutamate is known to be a hallmark of these diseases. Therefore, this study aims to evaluate the preventive effect of piceatannol on glutamate-induced neurodegeneration via mitochondrial rescue.
Subjects
Parkinson's disease; excitotoxicity; glutamate; neurodegeneration; piceatannol; resveratrol
SDGs
Type
journal article