Optimal Frequency of Hepatitis C Virus (HCV) RNA Testing for Detection of Acute HCV Infection Among At-risk People With Human Immunodeficiency Virus: A Multicenter Study
Journal
Open forum infectious diseases
Journal Volume
10
Journal Issue
6
Date Issued
2023-06
Author(s)
Liou, Bo-Huang
Chen, Tun-Chieh
Yang, Chia-Jui
Huang, Sung-Hsi
Lu, Po-Liang
Huang, Chung-Hao
Tsai, Mao-Song
Cheng, Shu-Hsing
Lee, Nan-Yao
Ko, Wen-Chien
Chen, Yen-Hsu
Lin, Shang-Yi
Lin, Shih-Ping
Chen, Po-Lin
Syue, Ling-Shan
Chen, Cheng-Bin
Chang, Ya-Ting
Lee, Yuan-Ti
Su, Li-Hsin
Cheng, Chien-Yu
Abstract
Using 3-stage pooled-plasma hepatitis C virus (HCV) RNA testing performed quarterly among at-risk people with human immunodeficiency virus (PWH), we found that if testing had been performed every 6 or 12 months, 58.6%-91.7% of PWH who recently acquired HCV would be delayed for diagnosis and might contribute to onward HCV transmission with longer durations.
Subjects
HCV RNA testing; HIV; acute HCV infection; testing frequency
SDGs
Type
journal article