Acute pancreatitis secondary to primary hyperparathyroidism in a postpartum patient: A case report and literature review
Journal
Taiwanese Journal of Obstetrics and Gynecology
Journal Volume
53
Journal Issue
2
Pages
252-255
Date Issued
2014
Author(s)
Abstract
Objective: Primary hyperparathyroidism (PHPT) is a rare clinical entity in reproductive women. Unusual hypercalcemia causing pancreatitis in the peripartum period carries significant morbidity to both the fetus and the mother. Case Report: A 38-year-old woman developed a morbid course of intractable intra-abdominal abscess by pancreatitis, hydronephrosis by renal lithiasis, and unusual neurological presentations soon after delivery. Serial serum calcium level and imaging studies lead to the final diagnosis of PHPT due to a parathyroid adenoma. Data on 14 patients who suffered from pancreatitis due to hyperparathyroidism were collected from a MEDLINE search. The reasons for delayed diagnosis and literature review of acute pancreatitis in PHPT are discussed. Conclusion: Hypercalcemia can be masked during pregnancy and in severe pancreatitis, as was detected in about half of the case series. Clinicians should have a high level of suspicion of parathyroid adenoma in cases with a profound pancreatitis. Timely diagnosis and early therapeutic intervention are important to resolve complications and improve the outcomes of mothers and fetuses. ? 2014.
Subjects
Hypercalcemia; Pancreatitis; Primary hyperparathyroidism
SDGs
Other Subjects
analgesic agent; calcium; diuretic agent; methoxy isobutyl isonitrile technetium tc 99m; pamidronic acid; abdominal abscess; abdominal pain; acute pancreatitis; adult; article; calcium blood level; case report; computer assisted tomography; delayed diagnosis; disease severity; epigastric pain; female; human; hydronephrosis; hypercalcemia; hyperparathyroidism; imaging; Medline; mother; nephrolithiasis; outcome assessment; parathyroid adenoma; parathyroidectomy; pregnancy; primary hyperparathyroidism; puerperium; abdominal abscess; acute disease; adenoma; complication; hypercalcemia; pancreatitis; Parathyroid Neoplasms; primary hyperparathyroidism; puerperium; Abdominal Abscess; Acute Disease; Adenoma; Adult; Female; Humans; Hypercalcemia; Hyperparathyroidism, Primary; Pancreatitis; Parathyroid Neoplasms; Postpartum Period
Type
journal article