The effect of time to neurosurgical or neuroradiological intervention therapy on outcomes and quality of care after traumatic brain injury, a registry-based observational study.
Journal
International journal of emergency medicine
Journal Volume
17
Journal Issue
1
ISSN
1865-1372
Date Issued
2024-12-20
Author(s)
Pansiritanachot, Wasin
Riyapan, Sattha
Shin, Sang Do
Chantanakomes, Jirayu
Thirawattanasoot, Netiporn
Rangabpai, Wichayada
Somboonkul, Bongkot
Jeong, Joo
Song, Kyoung Jun
Jamaluddin, Sabariah Faizah
Kajino, Kentaro
DOI
10.1186/s12245-024-00787-y
Abstract
Background: Evidence regarding the effect of time to neurosurgical and neuroradiological intervention on outcomes in traumatic brain injury (TBI) across Asia-Pacific region is limited. This study evaluates the quality of care and outcomes for TBI patients undergoing neurosurgical and neuroradiological procedures at different timings. Methods: Adult TBI patients who received any neurosurgical or neuroradiological interventions during the year 2015–2022 in the Pan-Asian Trauma Outcome Study database were analyzed. The time to intervention, as the main exposure, was classified into three groups (Early, Intermediate, and Delayed) using Restricted Cubic Spline (RCS) analysis. The outcomes were in-hospital mortality and unfavorable neurological outcomes. W score was utilized to compare the quality of care among exposure groups. Multivariable logistic regression analysis and interaction analysis were performed to identify the association between the exposure groups and outcomes, reported as adjusted odds ratios (AOR) with 95% confidence intervals (CI). Results: A total of 1,780 patients were included. From the RCS analysis, patients were classified into three groups according to time to intervention: Early (< 1.9 h), Intermediate (1.9–4.1 h), and Delayed (> 4.1 h). According to the time to intervention, W score was − 8.6 in the early group, -1.1 in the intermediate group, and + 0.4 in the delayed group. Patients receiving intermediate and delayed intervention showed significantly lower mortality (AOR 0.64, 95% CI 0.47–0.86 and AOR 0.66, 95%CI 0.48–0.90, respectively). Conclusion: Early neurosurgical and neuroradiological interventions in TBI patients in the Asia-Pacific region were associated with lower quality of care and higher mortality. The quality of care should be focused and improved during the early hours of TBI.
Subjects
Disability
Intervention
Mortality
Traumatic brain injury
Publisher
BioMed Central Ltd
Description
Article number 193
Type
journal article