Solitary vertebral collapse: Distinction between benign and malignant causes using MR patterns
Journal
Journal of Magnetic Resonance Imaging
Journal Volume
9
Journal Issue
5
Pages
635-642
Date Issued
1999
Author(s)
Abstract
Differentiation of benign from malignant causes of vertebral compression fracture can be difficult at a single location. We studied 37 patients with solitary vertebral collapse (SVC) in the spine using magnetic resonance imaging (MRI). Sixteen of them were found to have a benign cause of SVC, while the remaining 21 were found to have malignancy. The following four MRI characteristics were Investigated: ill- or well-defined margin of the intravertebral lesion (P < 0.005); pedicle involvement (P < 0.05); MR enhancement pattern (P < 0.005); and paravertebral soft tissue lesion (PSL) (P < 0.025). It was found that cases of malignant SVC tended to have an ill- defined margin, abnormal signal involvement of the pedicle, a marked and heterogenous MR enhancement pattern, and irregular nodular-type PSL. Pedicle change with expansile lesion totally excluded a benign cause. By using these criteria, we were able to differentiate benign or malignant causes of SVC accurately.
Subjects
Benign; Compression fracture; Malignant; Vertebra
SDGs
Other Subjects
contrast medium; gadolinium pentetate; adult; aged; article; bone metastasis; clinical article; contrast enhancement; differential diagnosis; female; human; intravenous drug administration; male; nuclear magnetic resonance imaging; priority journal; spine metastasis; spine tumor; vertebra body; vertebra fracture; Aged; Case-Control Studies; Diagnosis, Differential; Female; Fractures, Spontaneous; Humans; Lumbar Vertebrae; Magnetic Resonance Imaging; Male; Middle Aged; Spinal Diseases; Spinal Fractures; Spinal Neoplasms; Thoracic Vertebrae
Type
journal article