Dynamic changes in genetic diversity, drug resistance mutations, and treatment outcomes of falciparum malaria from the low-transmission to the pre-elimination phase on the islands of São Tomé and Príncipe
Journal
Malaria journal
Journal Volume
20
Journal Issue
1
Date Issued
2021-12-14
Author(s)
Abstract
With effective vector control and case management, substantial progress has been made towards eliminating malaria on the islands of São Tomé and Príncipe (STP). This study assessed the dynamic changes in the genetic diversity of Plasmodium falciparum, the anti-malarial drug resistance mutations, and malaria treatment outcomes between 2010 and 2016 to provide insights for the prevention of malaria rebounding.
Subjects
Antimalarial drug resistance mutations; Malaria; Merozoite surface proteins; Plasmodium falciparum; Recurrence; São Tomé and Príncipe
SDGs
Publisher
BMC
Type
journal article