Electroconvulsive Therapy for Shcizophrenic Patients
Resource
中華精神醫學 v.8 n.2 pp.91-95
Journal
中華精神醫學,v.8
Journal Issue
n.2
Pages
91-95
Date Issued
1994
Date
1994
Author(s)
CHEN, SHANG-YIH
HWU, HAI-GWO
CHANG, HSUEH-LING
LIN, HSIN-NAN
Abstract
As a second line treatment method for schizophrenic patients, elec- troconvulsive therapy (ECT) has been commonly used in Taiwan. However, there has been a lack of data documentation regarding times and seizure duration of ECT in schizophrenic patients. This research took the sample of 22 DSM-IIIR schizophrenic patients who were admitted to the acute psychiatric ward of the Department of Psychiatry, National Taiwan University, and who had the following clinical problems: (1) marked disturbing behavior due to psychopathological symptoms, (2) unsatisfactory therapeutic response of these psychopathological symptoms to neuroleptic treatment. Detailed clinical records were collected and analyzed. It was found that 15 cases (68.2%) had a favorable response to ECT. The therapeutic response was observed to begin after a mean of six ECT treatments, and a mean of 180 seconds of total seizure durations. On average, a single ECT induced seizure duration was about 30 seconds. favorable response rate than non- disorganized subtypes. No significant marked side effects of ECT were observed in this study sample. The implications of the study results in clinical and academic terms are discussed. 學界，以電痙攣治療為第二線治療方法治療精神分裂症之臨床作業，行之已久，但一 直沒有文獻資料，記載精神分裂症患者接受電痙攣治療時，所需電痙攣之劑量為多少 ?需多少次電痙攣治療?如果電痙攣治療有效，那是第幾次電痙攣治療後才可以觀察到 治療反應。本研究乃以台大醫院精神部22位因在病房有明顯之精神病理症狀引起嚴重 干擾行為，且其精神病理症狀對抗精神病劑的治療反應不佳，而接受電痙攣治療之 DSM-IIIR精神分裂症患者為研究樣本。仔細記載這些病患之臨床資料，電痙攣治療過 程，並予以分析。本研究發現15位(68.2%)患者有良好之電痙攣治療反應。其總電痙 攣治療次數平均值為14次，開始有治療反應之電痙攣治療次數與痙攣時間分別是6次 與180秒左右。平均每次電痙攣治療之痙攣時間約為30秒。此研究樣本中，沒有發現 特別之電痙攣治療副作用。本研究的發現，所蘊含之臨床與學術性意義，本文特予以 討論。