Developing a Vacuum-Actuated Peristaltic Micropump (VPM) with Inclined Wall Design to Achieve Low Hemolysis Blood Plasma Extraction
Journal
Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
Pages
1162
ISBN
9798350357929
Date Issued
2024-01-01
Author(s)
Abstract
There is a need for scalable, automated lab-on-chip systems for blood plasma separation that can be applied for diagnostics. Here, we developed a vacuum-actuated peristaltic micropump (VPM) integrating inertial microfluidic technique to separate and collect blood plasma from diluted blood. The device performs blood plasma separation with high efficiency (98.5%), quickly (<1 min), automatically, and with minimal whole blood usage (5 μL). Significantly, very little hemolysis (less than 2%) could be achieved using an inclined wall obstruction design in the vacuum actuator.
Subjects
Blood Plasma Separation | Hemolysis | Inertial Microfluidics | Micropump
Publisher
Institute of Electrical and Electronics Engineers Inc.
Type
conference paper