Cytogenetic study of mentally retarded children in Taipei
Journal
Journal of Biomedical Science
Journal Volume
1
Journal Issue
2
Pages
100-104
Date Issued
1994
Author(s)
Abstract
560 blood samples collected from mentally retarded children in Taipei were karyotypically analyzed for the incidence of fragile X and other chromosome abnormalities. The fragile site at Xq27.3 was observed in 18 patients (3.21%), 11 males and 7 females, out of the 560 blood cultures using M medium. Down syndrome (6.25%), 24 males and 11 females, was the other major category of abnormality. Other abnormalities, including inversion, translocation, deletion, duplication, ring as well as an extra marker chromosome were observed. The overall incidence of chromosomal abnormalities in these children was 14.82%. Copyright 1994 S. Karger AG, Basel
SDGs
Publisher
Kluwer Academic Publishers
Type
journal article