Essential Roles of the Histone Demethylase KDM4C in Renal Development and Acute Kidney Injury
Journal
International journal of molecular sciences
Journal Volume
23
Journal Issue
16
Date Issued
2022-08-18
Author(s)
Abstract
Lysine demethylase 4C (KDM4C) is a nuclear protein that is essential for histone modification and acts as an important regulator of several transcription factors. Previous studies have shown that KDM4C may also play a role in mediating stress responses. The purpose of this study was to examine the roles of KDM4C in kidney development and acute kidney injury (AKI).
Subjects
KDM4C; acute kidney injury; autophagy; ischemia reperfusion kidney injury; mitochondria
SDGs
Publisher
MDPI
Type
journal article