Hyperinakin, a new anti-inflammatory phloroglucinol derivative from Hypericum nakamurai
Journal
Natural Product Research
Journal Volume
27
Journal Issue
8
Pages
727-734
Date Issued
2013
Author(s)
Cheng Y.-B.
Fazary A.E.
Lin Y.-C.
Lo I.-W.
Ong S.-C.
Chen S.-Y.
Chien C.-T.
Lin Y.-J.
Shen Y.-C.
Abstract
Phytochemical investigation of Hypericum nakamurai (Masamune) Robson has led to the isolation of three phloroglucinol derivatives 1-3. The structures of these compounds were determined by the analysis of their spectroscopic data (IR, mass and UV), and by the application of 1-D and 2-D-NMR techniques. Hyperinakin (1) is a new compound. The anti-inflammatory activities of compounds 1-3 were also tested and evaluated. A biogenetic pathway for compounds 1-3 was also proposed.
Type
journal article