Novel Terpenoids from Calocedrus macrolepis var. formosana
Resource
CHEMISTRY & BIODIVERSITY, 8(10), 1901-1907
Journal
Chemistry & Biodiversity
Journal Volume
8
Journal Issue
10
Pages
1901-1907
Date Issued
2011
Date
2011
Author(s)
Hsieh, Chin-Lin
Tseng, Mei-Hwei
Pan, Ryh-Nan
Chang, Jang-Yang
Kuo, Ching-Chuan
Kuo, Yueh-Hsiung
Abstract
A new bisabolane-type sesquiterpene, trichoderic acid (1), and a new acorane-type sesquiterpene, 2β-hydroxytrichoacorenol (2), along with three known compounds, cyclonerodiol (3), cyclonerodiol oxide (4), and sorbicillin (5), were isolated from the culture broth of Trichoderma sp. PR-35, an endophytic fungus isolated from Paeonia delavayi. Their structures were elucidated on the basis of their IR, MS, and 1D- and 2D-NMR analyses. The antibacterial and antifungal activities of 1-5 towards various types of bacteria and fungi were tested. Most of the compounds showed moderate or weak antimicrobial activities in an agar-diffusion assay.
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Type
journal article
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