高血脂症是否會誘發心肌肥厚及其致病機轉(1/3)
Date Issued
2003
Date
2003
Author(s)
吳造中
DOI
912314B002283
Abstract
As the planning goal of this first year’s project, we established the research model of neonatal rat cardiomyocytes for studying the mechanisms of cardiac hypertrophy. In addition, we also purified low-density lipoprotein (LDL) from healthy donors’ blood. We oxidized the LDL under the catalysis of copper ion and attempted
to realize the acting mechanisms of oxidized LDL on cardiac myocytes when coronary artery disease occurred. Meanwhile, the signal transductional mechanisms of TNF-a induced ICAM-1 expression on endothelial cells were also under study.
Publisher
臺北市：國立臺灣大學醫學院一般醫學科
Type
journal article
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