HYPERURICEMIA AND METABOLIC SYNDROME IN TAIWANESE CHILDREN
Resource
ASIA PACIFIC JOURNAL OF CLINICAL NUTRITION v.16 pp.594-600
Journal
ASIA PACIFIC JOURNAL OF CLINICAL
Journal Volume
v.16
Journal Issue
NUTRITION
Pages
594-600
Date Issued
2007
Date
2007
Author(s)
Lee, Meei-Shyuan
Wahlqvist, Mark L.
Yu, Hsiao-Li
Pan, Wen-Harn
Abstract
Metabolic fitness in childhood is of increasing concern in
transitional and advanced economics as the metabolic
syndrome (MS) is recognized more often in this age group. As
the MS appears, so also does hyperuricemia. Studies in
Taiwan have identified both indigenous and Chinese with high
prevalence of hyperuricemia. Data (1227 boys and 1057 girls
, aged 6-12) from the Nutrition and Health Survey in Taiwan
Elementary School Children (NAHSIT Children 2001-2002) were
used to appraise the association between uric acid (UA) and
MS in children. Mean serum urate increases by age, ranging
from 5.69 mg/dL to 7.11 mg/dL for boys and 5.61 mg/dL to 6.
13 md/dL for girls. Boys have higher UA concentrations (6.07
mg/dL vs. 5.74 mg/dL) and hyperuricemia (UA >= 7 mg/dL)
rate (26.5% vs. 18.8%) than girls. Children of Mountain
areas have higher rates of hyperuricemia (boys: 39.2%, girls
: 30.1%). 5.56% of boys and 6.39% of girls were classified
as having the MS by ATP III criteria. Serum urate was
closely correlated with the MS parameters, and waist
circumference (WC) in particular (r = 0.387). WC alone
accounted for 18% of variance of serum urate concentration.
Both serum urate and hyperuricemia are significant risk
factors for the MS (serum urate in mg/dL, OR: 1.54, 95% CI:
1.36-1.74; hyperuricemia, OR: 3.73, 95% CI: 2.47-5.62).
Adjustment for age and region accentuate these relationships
. Not only abdominal fatness, but also uric acid status, or
both together may be of interest to public health workers
and clinicians in regard to the transitional health problem
of MS.
Subjects
serum urate
hyperuricemia
metabolic syndrome
abdominal obesity
elementary school children
Taiwan
Nutrition and Health Survey
SDGs
Type
journal article