調控脊髓基因對於針刺鎮痛之影響
Date Issued
2002
Date
2002
Author(s)
孫維仁
DOI
902314B002423
Abstract
In the present study, we examined the
effects of preoperative electroacupuncture (EA)
at classical bilateral acupuncture points
(Zusanli, also known as ST-36) on
postoperative pain and opioid-related side
effects. One hundred healthy consenting
women undergoing lower abdominal surgery
were randomly assigned to four treatment
regimens: Group I (n = 25), control; Group II (n
= 25), sham-EA (needle insertion without
electrical stimulation); Group III (n = 25),
low-EA (2 Hz of electrical stimulation); and
Group IV (n = 25), high-EA (100 Hz of
electrical stimulation). Electroacupuncture
groups received needle insertion with or
without electrical stimulation 20 minutes prior
to anesthesia. All patients received
patient-controlled analgesia (PCA) of morphine
postoperation. Postoperative pain was
evaluated by recording (1) the time of the first
required analgesic, (2) the number of PCA
demands, (3) the total amount of morphine
required by PCA, and (4) patients’ VAS pain
score. We found that the time of first analgesic
requested was 10 min, 18 min, 28 min, and 28
min in the control, sham-, low-, and high-EA
groups, respectively. During the first 24 h, the
total amount of morphine required was
decreased by 21%, 43% and 61% in the sham-,
low- and high-EA groups, respectively. The
incidence of nausea and dizziness during the
first 24 h after surgery was significantly
reduced in both the low-EA and high-EA
groups compared with the control and sham-EA
groups. We also found that sham-EA exerts a
beneficial effect with respect to its pain
relieving quality but not the side effect profiles.
Our findings demonstrates that preoperative
treatment with low-EA and high-EA can reduce
postoperative analgesic requirements and
associated side effects in patients undergoing
lower abdominal surgery.
Subjects
Electroacupuncture
Postoperative pain
Patient-controlled analgesia
Visual analogue
scale
scale
Publisher
臺北市：國立臺灣大學醫學院麻醉科
Type
journal article
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