Sulfated polysaccharides of Laetiporus sulphureus fruiting bodies exhibit anti-breast cancer activity through cell cycle arrest, apoptosis induction, and inhibiting cell migration
Journal
Journal of ethnopharmacology
Journal Volume
321
Date Issued
2024-03-01
Author(s)
Abstract
Laetiporus sulphureus has long been used as an edible and medicinal mushroom in Asia, America, and Europe. Its fruiting bodies are widely used in folk medicine for treating cancer, gastric diseases, cough, and rheumatism. Polysaccharides are an important bioactive component of mushrooms. In nature, sulfated polysaccharides have never been reported in mushrooms. Furthermore, there is no information on differences in physicochemical properties and anti-breast cancer activities between polysaccharides (PS) and sulfated polysaccharides (SPS) of L. sulphureus.
Subjects
Breast cancer cells; Cell cycle arrest; Laetiporus sulphureus; Physicochemical properties; Sulfated polysaccharides
SDGs
Type
journal article