Immunogenicity and safety of porcine circovirus-free human rotavirus vaccine in healthy infants: a phase III, randomized trial
Journal
The Journal of infectious diseases
Journal Volume
225
Journal Issue
12
Pages
2106
Date Issued
2020-05-04
Author(s)
Salamanca de la Cueva, Ignacio
Pahud, Barbara
Leonardi, Michael
Garcia-Sicilia, José
Céspedes, Javier
Abdelnour, Arturo
Tamura, Tsuyoshi
Kuroki, Haruo
Chiu, Nan-Chang
Virta, Miia
Kokko, Satu
Horn, Michael
Panzer, Falko
Kim, Jong-Hyun
Jin, Lee
Moerman, Leentje
Debacq, Christophe
Parra, Jose
Ugarte, Ana
Bi, Dan
Abstract
Porcine circovirus type 1 (PCV-1) material was detected in the human rotavirus vaccine (HRV) in 2010. In this study (NCT02914184) we compared immunogenicity and safety of the PCV-free HRV vaccine (PCV-free HRV) with HRV. PCV-free HRV is an HRV with no detection of PCV-1 and PCV-2 according to the limit of detection of the tests used.
Subjects
immunogenicity; porcine circovirus type 1; porcine circovirus-free; rotavirus vaccine; safety
Publisher
OXFORD UNIV PRESS INC
Type
journal article