Mechanical unfolding and refolding of proteins: An off-lattice model study
Journal
Physical Review E - Statistical, Nonlinear, and Soft Matter Physics
Journal Volume
63
Journal Issue
2 I
Pages
0219051-02190510
Date Issued
2001
Author(s)
Abstract
Using an off-lattice model, we investigate the response of a protein molecule to external stretching and release. In particular we study the passive force in a protein as a function of the extension of the protein. These force-extension curves exhibit hysteresis loops, whose areas increase with the pulling rate and decrease with thermal noise. Most of these results seem to be appropriately described by a cusp catastrophe.
Type
journal article