Tuberculous gumma (Cutaneous metastatic tuberculous abscess)
Journal
Dermatologica Sinica
Journal Volume
23
Journal Issue
1
Pages
27-31
Date Issued
2005
Author(s)
Abstract
Tuberculous gumma, also called metastatic tuberculous abscess, is a multibacillary type of skin tuberculosis caused by hematogenous spread of mycobacteria from a primary focus. We report a patient with tuberculous gumma on the right shin. The 68-year-old woman with pulmonary miliary tuberculosis and an occult non-Hodgkin lymphoma was found to have a pigeon-egg sized, soft nodule on the right shin. Histopathologic examination showed granulomatous inflammation with occasional giant cells and a pronounced inflammatory infiltrate in the deep dermis and subcutaneous tissue. Extensive necrosis with abscess formation was also noted. Acid-fast stain revealed multiple acid-fast bacilli. The tissue culture yielded Mycobacterium tuberculosis. The patient was treated with rifampin, isoniazid, pyrazinamide, and ethambutol daily for the initial 2 months, and isoniazid and rifampin for 4 more months. No recurrence of any skin lesion has been noted.
Subjects
Cutaneous metastatic tuberculous abscess; Tuberculous gumma
SDGs
Other Subjects
ethambutol; isoniazid; pyrazinamide; rifampicin; acid fast bacterium; aged; article; case report; cutaneous metastatic tuberculous abscess; dermis; female; giant cell; granulomatous inflammation; histopathology; human; inflammatory infiltrate; lung tuberculosis; miliary tuberculosis; Mycobacterium; Mycobacterium tuberculosis; nonhodgkin lymphoma; nonhuman; recurrence risk; skin abscess; skin necrosis; skin nodule; skin tuberculosis; subcutaneous tissue; tissue culture; treatment outcome; tuberculous gumma
Type
journal article