Residual urine output and postoperative mortality inmaintenance hemodialysis patients
Journal
American Journal of Critical Care
Journal Volume
18
Journal Issue
5
Pages
446-455
Date Issued
2009
Author(s)
Chen Y.-S.
Shiao S.C.
Wang W.-J.
Tsai P.-R.
Hu F.-C.
Abstract
Background: The relationship between residual urine output and postoperative survival in maintenance hemodialysis patients is unknown. Objective: To explore the relationship between amount of urine before surgery and postoperative mortality and differences between postoperative nonanuria and anuria in maintenance hemodialysis patients. Methods: A total of 109 maintenance hemodialysis patients underwent major operations. Anuria was defined as urine output <30 mL in the 8 hours before the first session of postoperative dial ysis. Propensity scores for postoperative anuria were developed. Results: Postoperative residual urine output was 159.2 mL/8 h (SD, 115.1) in 33 patients; 76 patients were anuric. Preoperative residual urine output and adequate perioperative blood transfusion were positively related to postoperative urine output. Propensity-adjusted 30-day mortality was associated with postoperative anuria (odds ratio [OR], 4.56; 95% confidence interval [CI], 1.16-17.96; P=.03), prior stroke (OR, 4.46; 95% CI, 1.43-13.89; P=.01) and higher disease severity (OR, 1.10; 95% CI, 1.00-1.21; P=.049) at the first postoperative dialysis. OR of 30-day mortality was 5.38 for nonanuria to anuria vs nonanuria to non anuria (P=.03) and 5.13 for preoperative anuria vs non anuria to nonanuria (P =.01). By Kaplan-Meier analysis, 30-day mortality differed significantly among patients for nonanuria to nonanuria, anuria, and nonanuria to anuria (log rank, P=.045). Conclusion Patients with preoperative nonanuria and postoperative anuria had higher mortality than did patients with no anuria before and after surgery and patients with anuria before surgery. Postoperative residual urine output is an important surrogate marker for disease severity. ? 2009 American Association of Critical-Care Nurses.
SDGs
Other Subjects
aged; anuria; article; chronic kidney failure; female; human; Kaplan Meier method; length of stay; male; middle aged; mortality; pathophysiology; postoperative complication; renal replacement therapy; statistical model; treatment outcome; Aged; Anuria; Female; Humans; Kaplan-Meier Estimate; Kidney Failure, Chronic; Length of Stay; Logistic Models; Male; Middle Aged; Postoperative Complications; Renal Dialysis; Treatment Outcome
Type
journal article