Long-term outcome after surgery for asymptomatic small hepatocellular carcinoma
Journal
British Journal of Surgery
Journal Volume
83
Journal Issue
3
Pages
330-333
Date Issued
1996
Author(s)
Abstract
The subjects of this study were 48 asymptomatic patients who had surgery for small hepatocellar carcinoma (HCC). There were 42 men and six women with mean (s.d.) tumour size of 3.31 (1.46) cm and age 55.0 (7.4) years. Follow-up was for a minimum of 10 years. The main concern of this study was a univariate analysis of factors that might affect long-term survival after surgery, which was 50 per cent at 5 years and 31 percent at 10 years. A high incidence of recurrent HCC (37 of 48 patients) was observed but reoperation further prolonged life in some cases. The significant prognostic factors detected by multivariate analysis were: histological classification, functional liver reserve and histology of the resection margin. Tumour size, gross appearance of tumour, presence of liver cirrhosis, serum α-fetoprotein level, age or sex did not affect the prognosis.
SDGs
Other Subjects
adult; article; cancer recurrence; cancer survival; clinical article; female; follow up; human; liver carcinoma; male; priority journal; prognosis; reoperation; treatment outcome; Carcinoma, Hepatocellular; Female; Follow-Up Studies; Humans; Liver Neoplasms; Male; Middle Aged; Multivariate Analysis; Survival Analysis; Survival Rate; Treatment Outcome
Type
journal article