Small Fiber Pathology in CADASIL: Clinical Correlation With Cognitive Impairment
Journal
Neurology
Journal Volume
99
Journal Issue
6
Pages
E583
End Page
E593
ISSN
0028-3878
Date Issued
2022-08-09
Author(s)
Abstract
This study investigated the cutaneous small fiber pathology of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) and its clinical significance, i.e. the NOTCH3 deposition in cutaneous vasculatures and CNS neurodegeneration focusing on cognitive impairment.
Subjects
CADASIL; cerebral small vessel disease; intraepidermal nerve fiber density; small fiber neuropathy; vascular cognitive impairment
SDGs
Publisher
LIPPINCOTT WILLIAMS & WILKINS
Type
journal article