Imaging biomarkers are underutilised but highly predictive prognostic factors for the more fatal breast cancer subtypes
Journal
European Journal of Radiology
Journal Volume
166
Date Issued
2023-09
Author(s)
Tabár, László
Dean, Peter B
Tucker, F Lee
Yen, Amy Ming-Fang
Chen, Sam Li-Sheng
Lin, Abbie Ting-Yu
Hsu, Chen-Yang
Munpolsri, Pattaranan
Wu, Wendy Yi-Ying
Smith, Robert A
Duffy, Stephen W
Tarján, Miklós
Vörös, András
Abstract
The development and refinement of breast imaging modalities offer a wealth of diagnostic information such as imaging biomarkers, which are primarily the mammographic appearance of the various breast cancer subtypes. These are readily available preoperatively at the time of diagnosis and can enhance the prognostic value of currently used molecular biomarkers. In this study, we investigated the relative utility of the molecular and imaging biomarkers, both jointly and independently, when predicting long-term patient outcome according to the site of tumour origin.
Subjects
Breast neoplasms; Early detection of cancer; Histopathology technology; Imaging biomarkers; Interdisciplinary communication; Mammography; Molecular biomarkers; Pathologists; Patient care; Precision medicine
Publisher
Elsevier Science Ireland Ltd
Type
journal article