Bacteria killing nanotechnology Bio-Kil effectively reduces bacterial burden in intensive care units
Journal
European Journal of Clinical Microbiology and Infectious Diseases
Journal Volume
33
Journal Issue
4
Pages
591-597
Date Issued
2014
Author(s)
Abstract
A contaminated hospital environment has been identified as an important reservoir of pathogens causing healthcare-associated infections. This study is to evaluate the efficacy of bacteria killing nanotechnology Bio-Kil on reducing bacterial counts in an intensive care unit (ICU). Two single-bed rooms (S-19 and S-20) in the ICU were selected from 7 April to 27 May 2011. Ten sets of new textiles (pillow cases, bed sheets, duvet cover, and patient clothing) used by patients in the two single-bed rooms were provided by the sponsors. In the room S-20, the 10 sets of new textiles were washed with Bio-Kil; the room walls, ceiling, and air-conditioning filters were treated with Bio-Kil; and the surfaces of instruments (respirator, telephone, and computer) were covered with Bio-Kil-embedded silicon pads. Room S-19 served as the control. We compared the bacterial count on textiles and environment surfaces as well as air samples between the two rooms. A total of 1,364 samples from 22 different sites in each room were collected. The mean bacterial count on textiles and environmental surfaces in room S-20 was significantly lower than that in room S-19 (10.4 vs 49.6 colony-forming units [CFU]/100 cm2; P<0.001). Room S-20 had lower bacterial counts in air samples than room S-19 (33.4-37.6 vs 21.6-25.7 CFU/hour/plate; P<0.001). The density of microbial isolations was significantly greater among patients admitted to room S-19 than those to room S-20 (9.15 vs 5.88 isolates per 100 patient-days, P<0.05). Bio-Kil can significantly reduce bacterial burden in the environment of the ICU. ? 2013 Springer-Verlag.
SDGs
Other Subjects
bio kill; disinfectant agent; unclassified drug; air sampling; article; Aspergillus; bacterial count; bacterial load; bactericidal activity; bacterium culture; bed; Candida; Clostridium difficile; environmental sanitation; hospital hygiene; human; intensive care unit; nanotechnology; priority journal; textile; devices; infection control; instrument sterilization; nanotechnology; procedures; Colony Count, Microbial; Humans; Infection Control; Intensive Care Units; Nanotechnology; Sterilization
Type
journal article