Transient Compartmentalization of Simian Immunodeficiency Virus Variants in the Breast Milk of African Green Monkeys

Ho, C; STEVEN HUNG-HSI WU; Amos, J.D; Colvin, L; Smith, S.D; Wilks, A.B; DeMarco, T; Brinkley, C; Denny, T.N; Schmitz, J.E; Rodrigo, A.G; Permar, S.R.; Ho, C;Wu, S;Amos, J.D;Colvin, L;Smith, S.D;Wilks, A.B;DeMarco, T;Brinkley, C;Denny, T.N;Schmitz, J.E;Rodrigo, A.G;Permar, S.R.

doi:10.1128/jvi.01643-13

Transient Compartmentalization of Simian Immunodeficiency Virus Variants in the Breast Milk of African Green Monkeys

Journal

Journal of Virology

Journal Volume

87

Date Issued

2013

Author(s)

Ho, C

STEVEN HUNG-HSI WU

Amos, J.D

Colvin, L

Smith, S.D

Wilks, A.B

DeMarco, T

Brinkley, C

Denny, T.N

Schmitz, J.E

Rodrigo, A.G

Permar, S.R.

DOI

10.1128/jvi.01643-13

URI

https://scholars.lib.ntu.edu.tw/handle/123456789/578170

URL

http://dx.doi.org/10.1128/jvi.01643-13

Abstract

Natural hosts of simian immunodeficiency virus (SIV), African green monkeys (AGMs), rarely transmit SIV via breast-feeding. In order to examine the genetic diversity of breast milk SIV variants in this limited-transmission setting, we performed phylogenetic analysis on
envelope sequences of milk and plasma SIV variants of AGMs. Low-diversity milk virus populations were compartmentalized from that in plasma. However, this compartmentalization was transient, as the milk virus lineages did not persist longitudinally.

SDGs

[SDGs]SDG15

Publisher

American Society for Microbiology

Type

journal article

File(s)

Name

Transient Compartmentalization of Simian Immunodeficiency Virus Variants in the Breast Milk of African Green Monkeys

Size

1020.37 KB

Format

Adobe PDF

Checksum

(MD5):9ea5c11417e14636e43d8694af26e993

Transient Compartmentalization of Simian Immunodeficiency Virus Variants in the Breast Milk of African Green Monkeys

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