Targeting the AXL signaling pathway in ovarian cancer
Journal
Molecular and Cellular Oncology
Journal Volume
4
Journal Issue
2
Pages
e1263716
Date Issued
2017
Author(s)
Abstract
In a recent publication in Science Signaling, we showed that a Mes molecular subtype of epithelial ovarian cancer (EOC) harboring epithelial-mesenchymal transition (EMT) features has a unique signaling network downstream of the GAS6/AXL pathway. Our finding leads to a potential strategy for treating the Mes subtype of EOC by targeting AXL.
SDGs
Publisher
Taylor and Francis Ltd.
Type
journal article