Metal-organic frameworks in diagnostics, therapeutics, and other biomedical applications
Journal
JOURNAL OF THE CHINESE CHEMICAL SOCIETY
Pages
1-13
Date Issued
2023
Author(s)
Abstract
Metal–organic frameworks (MOFs) are emerging porous coordination polymers constructed by metal ions and organic linkers that have attracted numerous interests in recent years. The large surface area, high porosity, tunable size, and versatile functionality make them promising materials for cargo delivery (i.e., drugs, mRNA, dyes) and sensing (i.e., nucleic acids, small molecules, ions). In addition, the metal ions released from MOFs offer antibacterial and antifungal utility. This review presents a snapshot of current MOF-related research, highlighting the synthesis approaches, and the various bioapplications of MOFs in terms of biosensing platforms, drug delivery, and antimicrobial agents, exposing potential for future research in the MOF field.
Subjects
antimicrobial; bioapplication; biosensor; drug delivery; metal-organic frameworks; MOFs; DNA; PLATFORM; MOF; ENCAPSULATION; MECHANISMS; SENSOR
Publisher
Chinese Chemical Society Taiwan
Type
review