Abrupt Decline in Estimated Glomerular Filtration Rate after Initiating Sodium-Glucose Cotransporter 2 Inhibitors Predicts Clinical Outcomes: A Systematic Review and Meta-Analysis
Journal
Diabetes & metabolism journal
Journal Volume
48
Journal Issue
2
Date Issued
2024-03
Author(s)
Chuang, Min-Hsiang
Tang, Yu-Shuo
Chen, Jui-Yi
Pan, Heng-Chih
Liao, Hung-Wei
Chu, Wen-Kai
Cheng, Chung-Yi
Heung, Michael
Abstract
The initiation of sodium-glucose cotransporter-2 inhibitors (SGLT2i) typically leads to a reversible initial dip in estimated glomerular filtration rate (eGFR). The implications of this phenomenon on clinical outcomes are not well-defined.
Subjects
Diabetes mellitus, type 2; Glomerular filtration rate; Kidney; Sodium-glucose transporter 2 inhibitors
SDGs
Type
journal article