Allergy accelerates the disease progression of chronic rhinosinusitis
Journal
Acta Oto-Laryngologica
Journal Volume
139
Journal Issue
1
Pages
75-79
Date Issued
2019
Author(s)
Abstract
Background: The role of allergy in the development of chronic rhinosinusitis (CRS) in East Asians is not clear. Aims/objectives: The aim was to investigate the impact of allergies in the clinical characteristics of chronic rhinosinusitis. Material and methods: A total of 138 CRS patients who underwent endoscopic sinus surgery were included. A brief history of rhinosinusitis symptoms, blood eosinophil count, blood-specific allergen tests, computed tomography (CT) scan findings, Lund-Mackay (LM) CT scores, and Sino-Nasal Outcome Test (SNOT-22) Questionnaire scores, and sinoscopy findings at 3 and 6?months postoperatively. Results: The ImmunoCAP test was positive in 71(51%) patients and negative in 67(49%) patients. The mean age of those who received endoscopic sinus surgery was 7-years younger in the allergic group compared with the non-allergic group (p =.008). The peripheral eosinophil count in the allergic group was higher than that of the non-allergic group (p =.008). The LM scores and SNOT-22 scores were not significantly different between the two groups. The recurrence rate of nasal polyps in the allergic group was higher but without statistical significance. Conclusions and significance: Allergy may accelerate the disease progression of CRS. The presence of the serum-specific IgE was correlated with peripheral eosinophil percentage, especially in the CRSwNP patients. ? 2019, ? 2019 Acta Oto-Laryngologica AB (Ltd).
Subjects
Allergy; chronic rhinosinusitis; eosinophil; Lund-Mackay score; SNOT-22
SDGs
Other Subjects
immunoglobulin E; adult; allergy; Article; asthma; atopic dermatitis; chronic rhinosinusitis; computer assisted tomography; disease course; disease severity; endoscopic sinus surgery; eosinophil count; female; human; immunoglobulin blood level; major clinical study; male; nose polyp; postoperative period; priority journal; recurrent disease; retrospective study; aged; allergic rhinitis; chronic disease; complication; disease exacerbation; middle aged; nose polyp; sinusitis; Adult; Aged; Chronic Disease; Disease Progression; Female; Humans; Male; Middle Aged; Nasal Polyps; Retrospective Studies; Rhinitis, Allergic; Sinusitis
Publisher
Taylor and Francis Ltd
Type
journal article