Frequency and Outcomes of Posthemorrhagic Ventricular Dilatation and Hydrocephalus in Preterm Infants with Intraventricular Hemorrhage
Journal
Clinical Neonatology
Journal Volume
14
Journal Issue
2
Pages
60
Date Issued
2007
Author(s)
Abstract
Background: Posthemorrhagic ventricular dilatation (PVD) and posthemorrhagic hydrocephalus (PHH) following intraventricular hemorrhage (IVH) are characteristic brain insults among preterm infants. The purpose of this study was to examine the incidence and risk factors of PVD/PHH in preterm infants who had IVH and their developmental outcomes based on the data collected at a medical center in Taiwan.Methods: From January 2003 through January 2005, preterm infants admitted to a medical center in northern Taiwan who developed IVH were enrolled in this study. Perinatal and postnatal data were collected via review of the medical records.Results: Of the 128 infants examined, the mean gestational age and birth weight were 29.1±3.5 weeks and 1266±493 g, respectively. Of the 69 infants who developed ventricular dilatation following IVH, 12 (18%) showed PHH and four (6%) received surgical intervention. Infants who had PVD/PHH showed lower gestational age, smaller birth weight, more severe IVH, and higher incidence of retinopathy of prematurity and periventricular leukomalacia than those who had no PVD/PHH. Furthermore, 59 (86%) showed arrest of ventricular dilatation including six with PHH. The mortality rate of preterm infants with PVD was 9%. All except one infant with PHH showed varied degrees of neurological sequelae during follow-up.Conclusions: Ventricular dilatation may occur in preterm infants who developed IVH during the neonatal period. Despite the high rate of arrest of ventricular dilatation, most of the infants with PHH manifested neurological sequelae during the follow-up period.
SDGs
Publisher
中華民國新生兒科醫學會
Type
journal article